Answer
Clearance may be slower in older people, critical illness and liver, kidney or cardiac impairment. CYP3A-inhibiting medicines can also prolong and intensify its effects.
Sources for this answer
- Midazolam 1mg/ml, solution for injection / infusion — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.