Answer
Cobicistat reduces tubular secretion of creatinine, causing a small early rise without necessarily reducing true glomerular function. Larger or progressive changes require assessment.
Sources for this answer
- Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Gilead 90 mg/90 mg/120 mg/6 mg film coated tablets — Current selected SmPCemc · Summary of Product Characteristics
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