Answer
Colestyramine binds ursodeoxycholic acid in the intestine, inhibiting its absorption and effectiveness, so the medicines should be taken at least 2 hours apart if colestyramine is necessary.
Sources for this answer
- Ursodeoxycholic Acid 300mg Film-Coated TabletsWockhardt UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 9Document updated
Sources checked