Answer
Bempedoic acid may increase serum creatinine by inhibiting OAT2-dependent renal tubular secretion of creatinine, a drug–endogenous substrate interaction that does not appear to indicate worsening kidney function and should be considered when interpreting estimated creatinine clearance.
Sources for this answer
- Nilemdo 180mg Film-coated TabletsDaiichi Sankyo UK Limited · emc · SmPC §4.8 Undesirable effects · Version 6Document updated
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