Answer
Systemically absorbed tobramycin is cleared through the kidneys and can damage renal function. Impaired clearance can increase kidney and hearing toxicity.
Sources for this answer
- Tobramycin 40mg/ml Injection — Current selected SmPCemc · Summary of Product Characteristics
- UK GovernmentUK Government · Reputable Web
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.