Answer
Both components are cleared through the kidneys, and tenofovir disoproxil can occasionally impair filtration or injure the renal tubules.
Sources for this answer
- Emtricitabine/Tenofovir disoproxil Dr. Reddy's 200 mg/245 mg Film-Coated Tablets — Current selected SmPCemc · Summary of Product Characteristics
- NHSNHS · NHS medicine guidance