Answer
Both components are cleared through the kidneys, and tenofovir disoproxil can occasionally cause renal impairment or proximal tubulopathy.
Sources for this answer
- Emtricitabine/Tenofovir disoproxil Milpharm 200 mg/245 mg Film-coated Tablets — Current selected SmPCemc · Summary of Product Characteristics
- NHSNHS · NHS medicine guidance