Answer
Histergan tablets containing diphenhydramine hydrochloride are not recommended during pregnancy because diphenhydramine crosses the placenta, human pregnancy experience is inadequate and risks are unknown, animal studies may not predict human responses, and third-trimester sedating antihistamine use may cause reactions in newborns or premature neonates.
Sources for this answer
- Histergan TabletsNorma Chemicals Limited · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 1Document updated
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