Answer
Trametinib can reduce the heart's pumping function. Echocardiography or another LVEF assessment helps detect this before symptoms become severe.
Sources for this answer
- Mekinist film-coated tablets — Current selected SmPCemc · Summary of Product Characteristics
- Spexotras 0.05 mg/ml powder for oral solution — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.