Which serotonin receptor does prucalopride selectively activate?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Prucalopride selectively activates the serotonin 5-HT4 receptor as a high-affinity agonist.

Resolor 1mg film-coated tabletsTakeda UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 19Document updated 22 December 2022

Sources checked 8 November 2026

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prucalopride succinate · Medicine question

iatroX medicinesPublished 8 November 2026

The answer

Prucalopride selectively activates the serotonin 5-HT4 receptor as a high-affinity agonist.

Resolor 1mg film-coated tabletsTakeda UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 19Document updated 22 December 2022

Sources checked 8 November 2026

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