Answer
Bevacizumab prevents VEGF from binding to Flt‑1 (VEGFR-1) and KDR (VEGFR-2) receptors on the surface of endothelial cells.
Sources for this answer
- Avastin 25mg/ml concentrate for solution for infusionRoche Products Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 64Document updated
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