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Medicines pertuzumabQuestion & answer

pertuzumab · Medicine question

Which part of the HER2 receptor does pertuzumab bind to?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Pertuzumab binds to the extracellular dimerization domain (subdomain II) of the HER2 receptor.

Sources for this answer

Perjeta 420 mg Concentrate for Solution for InfusionRoche Products Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 22Document updated 16 June 2026

Sources checked 8 November 2026

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pertuzumab

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