nortriptyline hydrochloride · Medicine question

Which neurotransmitter's reuptake does nortriptyline inhibit more strongly, noradrenaline or serotonin?

Name: Which neurotransmitter's reuptake does nortriptyline inhibit more strongly, noradrenaline or serotonin?
Published: 2026-11-08T14:25:09.207Z

iatroX medicinesPublished 8 November 2026

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Answer

Nortriptyline inhibits presynaptic noradrenaline reuptake more strongly than serotonin reuptake.

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Nortriptyline 10 mg film-coated tabletsBrown & Burk UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 4Document updated 22 January 2025

Sources checked 8 November 2026

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