Answer
In INEGY, ezetimibe targets the sterol transporter Niemann-Pick C1-Like 1 (NPC1L1), while simvastatin, after conversion in the liver to its active β-hydroxyacid form, inhibits HMG-CoA reductase.
Sources for this answer
- INEGY TabletsOrganon Pharma (UK) Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 38Document updated
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