Answer
All medicines should be reviewed. Methotrexate, tizanidine and similar narrow-therapeutic-index medicines are particularly important because aprocitentan may alter their exposure.
Sources for this answer
- JERAYGO 12.5 mg film-coated tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.