Answer
Moderate or strong CYP3A4 inducers—including rifamycins, carbamazepine, phenytoin, efavirenz, etravirine and St John's wort—may reduce bedaquiline exposure and should generally be avoided.
Sources for this answer
- Sirturo 100 mg tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.