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Medicines RuxolitinibQuestion & answer

Ruxolitinib · Medicine question

Which Janus kinase enzymes does ruxolitinib inhibit?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Ruxolitinib selectively inhibits the Janus kinase enzymes JAK1 and JAK2.

Sources for this answer

Opzelura 15 mg/g creamIncyte Biosciences UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 4Document updated 7 May 2026

Sources checked 8 November 2026

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Ruxolitinib

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