infliximab · Medicine question

Which forms of tumour necrosis factor alpha (TNF-alpha) does infliximab bind to?

Name: Which forms of tumour necrosis factor alpha (TNF-alpha) does infliximab bind to?
Published: 2026-11-08T14:24:06.781Z

iatroX medicinesPublished 8 November 2026

The answer

Answer

Infliximab binds with high affinity to both soluble and transmembrane forms of TNF-alpha, but not to lymphotoxin-alpha (TNF-beta).

Remicade 100mg powder for concentrate for solution for infusionJanssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §5.1 Pharmacodynamic properties · Version 75Document updated 30 July 2025

Sources checked 8 November 2026

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