Answer
Prograf (tacrolimus) 5 mg/ml concentrate for solution for infusion must be diluted with 5% w/v glucose or physiological saline in polyethylene, polypropylene or glass, never PVC, using only transparent, colourless solutions, to 0.004–0.100 mg/ml and 20–500 ml per 24 hours; do not inject undiluted or administer as a bolus.
Sources for this answer
- Prograf 5mg/ml Concentrate for Solution for Infusion (UK)Astellas Pharma Ltd · emc · SmPC §6.6 Special precautions for disposal and other handling · Version 29Document updated
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