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Medicines lapatinib ditosylate monohydrateQuestion & answer

lapatinib ditosylate monohydrate · Medicine question

Which enzymes primarily metabolise lapatinib?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Lapatinib is primarily metabolised by CYP3A4 and CYP3A5, with minor contributions from CYP2C19 and CYP2C8.

Sources for this answer

Tyverb film-coated tabletsNovartis Pharmaceuticals UK Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 34Document updated 15 June 2022

Sources checked 8 November 2026

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lapatinib ditosylate monohydrate

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