Answer
The active triphosphate metabolite of fludarabine phosphate, 2F-ara-ATP, inhibits ribonucleotide reductase, DNA polymerases α/δ and ε, DNA primase and DNA ligase.
Sources for this answer
- Fludara oral 10 mg film-coated tabletSANOFI · emc · SmPC §5.1 Pharmacodynamic properties · Version 27Document updated
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