Answer
Cytochrome P450 3A4 mediates bupivacaine’s main liver metabolic pathways: aromatic hydroxylation to 4-hydroxybupivacaine and N-dealkylation to PPX.
Sources for this answer
- Bupivacaine Heavy 5 mg/ml Solution for InjectionPanpharma UK Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 2Document updated
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