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Medicines idelalisibQuestion & answer

idelalisib · Medicine question

Which enzyme is primarily responsible for metabolising idelalisib?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Idelalisib is metabolised primarily by aldehyde oxidase, with lesser contributions from CYP3A and UGT1A4.

Sources for this answer

Zydelig 150mg film-coated tabletsGilead Sciences Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 23Document updated 4 February 2025

Sources checked 8 November 2026

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idelalisib

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