Answer
Cytochrome P450 CYP1A2 is involved in the hepatic metabolism of bendamustine, forming N-desmethyl-bendamustine and gamma-hydroxy-bendamustine.
Sources for this answer
- Bendamustine hydrochloride 180 mg/4 ml Concentrate For Solution For InfusionDr. Reddy's Laboratories (UK) Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 8Document updated
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