Answer
In vitro studies indicate that bortezomib is primarily oxidatively metabolised by cytochrome P450 enzymes CYP3A4, CYP2C19 and CYP1A2.
Sources for this answer
- Velcade 3.5mg powder for solution for injection (Great Britain)Janssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §5.2 Pharmacokinetic properties · Version 37Document updated
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