iptacopan hydrochloride monohydrate · Medicine question

Which complement protein does Fabhalta (iptacopan) target, and which pathway does it selectively inhibit?

Name: Which complement protein does Fabhalta (iptacopan) target, and which pathway does it selectively inhibit?
Published: 2026-11-08T14:24:57.994Z

iatroX medicinesPublished 8 November 2026

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Answer

Fabhalta (iptacopan) targets complement Factor B to selectively inhibit the alternative complement pathway.

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FABHALTA 200 mg hard capsulesNovartis Pharmaceuticals UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 4Document updated 18 March 2026

Sources checked 8 November 2026

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