Answer
The chimeric antigen receptor in ciltacabtagene autoleucel (CARVYKTI) contains a 4-1BB co-stimulatory domain and a CD3-zeta (CD3ζ) signalling cytoplasmic domain.
Sources for this answer
- CARVYKTI 3.2 × 10^6 – 1 × 10^8 cells dispersion for infusionJanssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §5.1 Pharmacodynamic properties · Version 6Document updated
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