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Medicines palbociclibQuestion & answer

palbociclib · Medicine question

Which cell-cycle transition does palbociclib block?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Palbociclib blocks progression from G1 into S phase of the cell cycle through inhibition of CDK4/6.

Sources for this answer

IBRANCE 75 mg film-coated tabletsPfizer Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 10Document updated 3 January 2025

Sources checked 8 November 2026

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The full medicine guide

palbociclib

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