ivabradine hydrochloride · Medicine question

Which cardiac pacemaker current does ivabradine inhibit to lower heart rate?

Name: Which cardiac pacemaker current does ivabradine inhibit to lower heart rate?
Published: 2026-11-08T14:18:10.616Z

iatroX medicinesPublished 8 November 2026

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Answer

Ivabradine selectively and specifically inhibits the cardiac pacemaker I_f current, which controls spontaneous diastolic depolarisation in the sinus node and regulates heart rate.

Sources for this answer

ProcoralanServier Laboratories Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 22Document updated 5 January 2022

Sources checked 8 November 2026

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