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Medicines nefopam hydrochlorideQuestion & answer

nefopam hydrochloride · Medicine question

Which antidepressants interact with nefopam hydrochloride?

iatroX medicinesPublished 21 August 2026Reviewed 21 August 2026

The answer

Answer

Monoamine oxidase inhibitors must not be combined with nefopam. Tricyclic antidepressants such as amitriptyline require caution.

Sources for this answer

Nefopam hydrochloride 30 mg Film-coated Tabletsemc · SmPC Current selected SmPC · Version 2
NHSNHS · NHS medicine guidance

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nefopam hydrochloride

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