Answer
The most frequently reported adverse reactions in clinical studies of Advate (octocog alfa) were development of neutralising antibodies to factor VIII (inhibitors), headache and fever.
Sources for this answer
- ADVATE 250 IU, 500 IU,1000 IU, 1500 IU, 2000 IU and 3000 IU powder and solvent for solution for injection 5 ml solventTakeda UK Ltd · emc · SmPC §4.8 Undesirable effects · Version 14Document updated
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