Answer
After taking Lizinna (ethinylestradiol + norgestimate), norgestimate is rapidly metabolised by intestinal and/or hepatic first-pass mechanisms to norelgestromin and norgestrel, both pharmacologically active progestogens.
Sources for this answer
- Lizinna 250 microgram /35 microgram TabletsMorningside Healthcare Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 6Document updated
Sources checked