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Medicines crizotinibQuestion & answer

crizotinib · Medicine question

Where in the body is crizotinib extensively metabolised?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Crizotinib is extensively metabolised in the liver.

Sources for this answer

Xalkori 200mg hard capsulePfizer Limited · emc · SmPC §4.2 Posology and method of administration · Version 37Document updated 25 February 2025

Sources checked 8 November 2026

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The full medicine guide

crizotinib

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More questions about crizotinib

How are Xalkori crizotinib granules administered after opening the capsule?What specialist experience is required of the physician initiating and supervising Xalkori crizotinib treatment?Which adverse effects most frequently led to crizotinib treatment interruptions in adults with ALK-positive or ROS1-positive NSCLC in clinical studies?Why should grapefruit and grapefruit juice be avoided while taking crizotinib?What allergy-related contraindication applies to Xalkori crizotinib capsules?

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