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Medicines durvalumabQuestion & answer

durvalumab · Medicine question

What thyroid disorders can durvalumab cause?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Durvalumab (Imfinzi) can cause immune-mediated hypothyroidism, hyperthyroidism and thyroiditis, and hypothyroidism may follow hyperthyroidism.

Sources for this answer

IMFINZI 50 mg/mL concentrate for solution for infusionAstraZeneca UK Limited · emc · SmPC §4.4 Special warnings and precautions for use · Version 38Document updated 6 May 2026

Sources checked 8 November 2026

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Can durvalumab cause immune-mediated colitis or diarrhoea?Can durvalumab cause immune-mediated pneumonitis or interstitial lung disease?Can durvalumab cause type 1 diabetes that first presents as diabetic ketoacidosis?Which liver blood tests should be monitored before starting durvalumab and before each subsequent infusion?How is durvalumab (Imfinzi) administered, and how long does the infusion take?What should durvalumab (Imfinzi) concentrate for solution for infusion look like?

durvalumab

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