What systemic corticosteroid risks are associated with using inhaled or nasal fluticasone propionate with Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil Gilead?

Using inhaled or nasal fluticasone propionate with Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil Gilead may increase systemic corticosteroid effects, including Cushing's syndrome and adrenal suppression; co-administration is not recommended unless benefits outweigh risks, with monitoring required if used.