Answer
The opioid component of Paramol Tablets can cause central sleep apnoea (CSA) and sleep-related hypoxemia, with CSA risk increasing dose-dependently; if CSA occurs, opioid dose reduction using best practices for tapering should be considered.
Sources for this answer
- Paramol TabletsReckitt Benckiser Healthcare (UK) Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 9Document updated
Sources checked