Answer
Very rare cases of serious hepatotoxicity, including fatal acute liver failure, have been reported with itraconazole, sometimes without pre-existing liver disease and sometimes within the first week of treatment.
Sources for this answer
- Itraconazole 10mg/ml Sugar Free Oral SolutionSyriMed · emc · SmPC §4.4 Special warnings and precautions for use · Version 6Document updated
Sources checked