Answer
Combining Epistatus (midazolam maleate) with opioids increases the risk of sedation, respiratory depression, coma and death through additive central nervous system depression, so the dosage and duration of concomitant use should be limited.
Sources for this answer
- Epistatus 10mg oromucosal solutionSERB · emc · SmPC §4.5 Interaction with other medicinal products · Version 1Document updated
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