Answer
Hyalase (hyaluronidase) should be avoided during pregnancy unless there is no safer alternative, because there is no evidence of safety in human pregnancy or evidence from animal studies that it is free from hazard.
Sources for this answer
- Hyalase 1500 I.U. Powder for Solution for Injection/Infusion or Hyaluronidase 1500 I.U. Powder for Solution for Injection/InfusionWockhardt UK Ltd · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 7Document updated
Sources checked