Answer
Cayston (aztreonam lysine) should be used cautiously in renal impairment with serum creatinine above twice the upper limit of normal because aztreonam is renally excreted, but no dose adjustment is necessary because systemic concentrations after inhalation are very low.
Sources for this answer
- Cayston 75 mg powder and solvent for nebuliser solutionGilead Sciences Ltd · emc · SmPC §4.2 Posology and method of administration · Version 20Document updated
Sources checked