Answer
Metvix product information reports mean cumulative absorption of radiolabelled methyl aminolevulinate through human skin of 0.26% of the administered dose after 24 hours in vitro; corresponding studies were not performed in skin with actinic-keratosis-like damage and an additionally roughened surface, or without stratum corneum.
Sources for this answer
- Metvix 160 mg/g creamGalderma (U.K.) Limited · emc · SmPC §5.2 Pharmacokinetic properties · Version 23Document updated
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