Answer
Convulsions, worsening of convulsions, increased excitability and irritability have been observed during combined sapropterin dihydrochloride and levodopa treatment in patients with BH4 deficiency, so caution is required when prescribing them together.
Sources for this answer
- Sapropterin dihydrochloride 100 mg Soluble TabletsTeva UK Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 1Document updated
Sources checked