Answer
Cosmegen (dactinomycin) requires the two-needle technique for direct intravenous injection without an infusion: reconstitute and withdraw the calculated dose from the vial with one sterile needle, then inject into the vein with another sterile needle.
Sources for this answer
- Cosmegen Lyovac 500 micrograms powder for solution for injectionRecordati Rare Diseases UK Ltd · emc · SmPC §4.2 Posology and method of administration · Version 5Document updated
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