Answer
Hepatotoxicity, mainly increased liver enzymes, has been reported with perampanel combined with other antiepileptic medicines; liver-function monitoring should be considered if liver enzymes rise.
Sources for this answer
- Perampanel Eisai 2mg film-coated tabletsEisai Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 23Document updated
Sources checked