What is the terminal elimination half-life of melatonin in Circadin prolonged-release tablets?

iatroX medicinesPublished 8 November 2026

The answer

Answer

The terminal elimination half-life of melatonin in Circadin prolonged-release tablets is 3.5–4 hours.

CircadinFlynn Pharma Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 12Document updated 11 February 2025

Sources checked 8 November 2026

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melatonin · Medicine question

iatroX medicinesPublished 8 November 2026

The answer

The terminal elimination half-life of melatonin in Circadin prolonged-release tablets is 3.5–4 hours.

CircadinFlynn Pharma Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 12Document updated 11 February 2025

Sources checked 8 November 2026

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