Answer
Otrivine Blocked Nose Relief 0.1% Nasal Spray containing xylometazoline hydrochloride has a shelf life of 36 months, and first opening does not shorten it: the spray can be used until the end of its shelf life.
Sources for this answer
- Otrivine Sinusitis Relief, 0.1% w/v Nasal Spray, Solution / Otrivine Blocked Nose Relief, 0.1% w/v Nasal Spray, Solution /Otrivine Allergy Relief, 0.1% Nasal SprayHaleon UK Trading Limited · emc · SmPC §6.3 Shelf life · Version 15Document updated
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