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Medicines vedolizumabQuestion & answer

vedolizumab · Medicine question

What is the serum half-life of vedolizumab?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Vedolizumab has a serum half-life of 26 days, based on population pharmacokinetic analyses of intravenous and subcutaneous data.

Sources for this answer

Entyvio 300 mg powder for concentrate for solution for infusionTakeda UK Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 17Document updated 26 May 2026

Sources checked 8 November 2026

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The full medicine guide

vedolizumab

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What is the shelf life of unopened Entyvio (vedolizumab) 300 mg powder for concentrate for solution for infusion?Can Entyvio (vedolizumab) 300 mg powder for concentrate for solution for infusion be mixed with other medicinal products?Does concomitant methotrexate have a clinically meaningful effect on vedolizumab pharmacokinetics in adults with ulcerative colitis or Crohn’s disease?How long does an intravenous infusion of Entyvio (vedolizumab) 300 mg take?How many vials are in each pack of Entyvio (vedolizumab) 300 mg powder for concentrate for solution for infusion?

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