Answer
Carbamazepine’s mechanism is only partially understood, but its proposed main action is use- and voltage-dependent sodium-channel blockade, preventing repetitive firing of sodium-dependent action potentials in depolarised neurons.
Sources for this answer
- Tegretol Tablets 100mg, 200mg, 400mgNovartis Pharmaceuticals UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 36Document updated
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