Answer
Metoclopramide’s plasma elimination half-life is 5–6 hours irrespective of administration route, increasing with renal impairment to approximately 10 hours at creatinine clearance 10–50 ml/minute and 15 hours below 10 ml/minute.
Sources for this answer
- Metoclopramide hydrochloride 5mg/5ml Oral SolutionSyriMed · emc · SmPC §5.2 Pharmacokinetic properties · Version 6Document updated
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