Answer
The maximum single subcutaneous injection volume of Oxlumo (lumasiran sodium) is 1.5 mL; larger doses must be divided equally between syringes and administered as multiple injections of approximately equal volume to minimise injection-site discomfort.
Sources for this answer
- Oxlumo 94.5 mg/0.5 mL solution for injectionAlnylam UK Ltd · emc · SmPC §4.2 Posology and method of administration · Version 8Document updated
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